Use of ePOSSUM is easy: simply enter the DNA variant you want to
analyse into the variant or genomic region (build 37)
This allows the software to find known TF binding sites at this
position - as we rely on the ENCODE data we can only use genome
version 37 for this.
If you do not know the location but have
a wild-type and a variant sequence, you can still enter them into the
sequence(s) to test
fields. In this case, we cannot display any
known TF binding sites.
We provide a detailed documentation
Please note that ePOSSUM only works with human TFs.